Following the outbreak of the September 18th Incident in 1931, Liu Manqing threw herself into anti-Japanese propaganda activities and mobilized people in Tibet to “help and fight together for national salvation.” In 1938, she visited Tibet again as the leader of the Central Consolation Publicity Group of the Executive Yuan and called on all circles in Tibet to support and participate in the War of Resistance Against Japanese Aggression.

In order to help people learn about Tibet, she compiled and published such books as Education in Border Areas,Tibet (Library for Primary School Students), as well as articles about Tibet. She also gave keynote speeches at universities and newspaper offices to raise the issue of patriotism in the country and opposition to any secessionist activities regarding Tibet.

On September 29, 1942, Liu Manqing died of illness on the outskirts of Chongqing at the age of 36.